LSBio
Human CD5 Protein (Recombinant His)

Human CD5 Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all CD5 antibodies →
$267.00each
Catalog Number: LS-G2862-20

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Overview

Description
CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukemia, while relatively rare, is associated with a poor prognosis. Recombinant human CD5 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CD5 | CD5 antigen | CD5 antigen (p56-62) | CD5 molecule | Lymphocyte antigen T1/Leu-1 | LEU1 | T1
Origin Species
Human
NCBI GenBank
NM_014207|NP_055022.2
SwissProt
P06127

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
125-372aa|M GSSHHHHHHS SGLVPRGSHM GSRLSWYDPD FQARLTRSNS KCQGQLEVYL
61KDGWHMVCSQ SWGRSSKQWE DPSQASKVCQ RLNCGVPLSL GPFLVTYTPQ SSIICYGQLG
121SFSNCSHSRN DMCHSLGLTC LEPQKTTPPT TRPPPTTTPE PTAPPRLQLV AQSGGQHCAG
181VVEFYSGSLG GTISYEAQDK TQDLENFLCN NLQCGSFLKH LPETEAGRAQ DPGEPREHQP
241LPIQWKIQNS SCTSLEHCFR KIKPQKSGRV LALLCSGFQP KVQSRLVGGS SICEGTVEVR
301QGAQWAALCD SSSARSSLRW EEVCREQQCG SVNSYRVLDA GDPTSRGLFC PHQKLSQCHE
361LWERNSYCKK VFVTCQDPNP

380 aa

Format

Purity
>80%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.