CD38 Antibody (clone ABT-CD38)
Catalog Number: LS-C744468
4 sizes / from $274.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Human CD38 Protein (Recombinant mFc, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$328.00each
Catalog Number: LS-G137901-10
Catalog Number: LS-G137901
For bulk orders or custom formulations:
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- Description
- CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ADP-ribosyl cyclase 1 | CD38 antigen (p45) | CD38 antigen | Cyclic ADP-ribose hydrolase 1 | T10 | CADPr hydrolase 1 | CD38 | CD38 molecule | NAD(+) nucleosidase
- Origin Species
- Human
- NCBI GenBank
- NM_001775
- SwissProt
- P28907
Protein
- Expression System
- Other
- Fusion Tag
- Mouse Fc Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1VPRWRQQWSG PGTTKRFPET VLARCVKYTE IHPEMRHVDC QSVWDAFKGA FISKHPCNIT61EEDYQPLMKL GTQTVPCNKI LLWSRIKDLA HQFTQVQRDM FTLEDTLLGY LADDLTWCGE121FNTSKINYQS CPDWRKDCSN NPVSVFWKTV SRRFAEAACD VVHVMLNGSR SKIFDKNSTF181GSVEVHNLQP EKVQTLEAWV IHGGREDSRD LCQDPTIKEL ESIISKRNIQ FSCKNIYRPD241KFLQCVKNPE DSSCTSEIVD DIEGRMDPRD CGCKPCICTV PEVSSVFIFP PKPKDVLTIT301LTPKVTCVVV DISKDDPEVQ FSWFVDDVEV HTAQTQPREE QFNSTFRSVS ELPIMHQDWL361NGKEFKCRVN SAAFPAPIEK TISKTKGRPK APQVYTIPPP KEQMAKDKVS LTCMITDFFP421EDITVEWQWN GQPAENYKNT QPIMDTDGSY FVYSKLNVQK SNWEAGNTFT CSVLHEGLHN481HHTEKSLSHS PGK
493 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
