CD38 Antibody (clone ABT-CD38)
Catalog Number: LS-C744468
4 sizes / from $274.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Human CD38 Protein (Recombinant Fc, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$328.00each
Catalog Number: LS-G137861-10
Catalog Number: LS-G137861
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- Description
- CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ADP-ribosyl cyclase 1 | CD38 antigen (p45) | CD38 antigen | Cyclic ADP-ribose hydrolase 1 | T10 | CADPr hydrolase 1 | CD38 | CD38 molecule | NAD(+) nucleosidase
- Origin Species
- Human
- NCBI GenBank
- NM_001775
- SwissProt
- P28907
Protein
- Expression System
- Other
- Fusion Tag
- Human IgG1 Fc Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1VPRWRQQWSG PGTTKRFPET VLARCVKYTE IHPEMRHVDC QSVWDAFKGA FISKHPCNIT61EEDYQPLMKL GTQTVPCNKI LLWSRIKDLA HQFTQVQRDM FTLEDTLLGY LADDLTWCGE121FNTSKINYQS CPDWRKDCSN NPVSVFWKTV SRRFAEAACD VVHVMLNGSR SKIFDKNSTF181GSVEVHNLQP EKVQTLEAWV IHGGREDSRD LCQDPTIKEL ESIISKRNIQ FSCKNIYRPD241KFLQCVKNPE DSSCTSEIVD DIEGRMDEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK301DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV361LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSREEM TKNQVSLTCL421VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM481HEALHNHYTQ KSLSLSPGK
499 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
