LSBio
Human CD38 Protein (Recombinant 6His, C-terminus)

Human CD38 Protein (Recombinant 6His, C-terminus)

Expression SystemOther
Format:Lyophilized
See all CD38 antibodies →
$328.00each
Catalog Number: LS-G137868-10

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Overview

Description
CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
ADP-ribosyl cyclase 1 | CD38 antigen (p45) | CD38 antigen | Cyclic ADP-ribose hydrolase 1 | T10 | CADPr hydrolase 1 | CD38 | CD38 molecule | NAD(+) nucleosidase
Origin Species
Human
NCBI GenBank
NM_001775
SwissProt
P28907

Protein

Expression System
Other
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
1VPRWRQQWSG PGTTKRFPET VLARCVKYTE IHPEMRHVDC QSVWDAFKGA FISKHPCNIT
61EEDYQPLMKL GTQTVPCNKI LLWSRIKDLA HQFTQVQRDM FTLEDTLLGY LADDLTWCGE
121FNTSKINYQS CPDWRKDCSN NPVSVFWKTV SRRFAEAACD VVHVMLNGSR SKIFDKNSTF
181GSVEVHNLQP EKVQTLEAWV IHGGREDSRD LCQDPTIKEL ESIISKRNIQ FSCKNIYRPD
241KFLQCVKNPE DSSCTSEIHH HHHH

264 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Store at < -20°C for up to 6 months. Avoid freeze-thaw cycles.

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