LSBio
Human ARSA / Arylsulfatase A Protein (Recombinant His)

Human ARSA / Arylsulfatase A Protein (Recombinant His)

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Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all ARSA antibodies →
$267.00each
Catalog Number: LS-G2306-20

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Overview

Description
ARSA hydrolyzes cerebrosidesulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. Recombinant human ARSA protein, fused to His-tag at N-terminus, was expressed in E.coli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Arylsulfatase A | Cerebroside-sulfatase | MLD | ARSA | ASA
Origin Species
Human
NCBI GenBank
NM_000487|NP_000478.3
SwissProt
P15289

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
121-509aa|M GSSHHHHHHS SGLVPRGSHM GSRPPNIVLI FADDLGYGDL GCYGHPSSTT
61PNLDQLAAGG LRFTDFYVPV SLCTPSRAAL LTGRLPVRMG MYPGVLVPSS RGGLPLEEVT
121VAEVLAARGY LTGMAGKWHL GVGPEGAFLP PHQGFHRFLG IPYSHDQGPC QNLTCFPPAT
181PCDGGCDQGL VPIPLLANLS VEAQPPWLPG LEARYMAFAH DLMADAQRQD RPFFLYYASH
241HTHYPQFSGQ SFAERSGRGP FGDSLMELDA AVGTLMTAIG DLGLLEETLV IFTADNGPET
301MRMSRGGCSG LLRCGKGTTY EGGVREPALA FWPGHIAPGV THELASSLDL LPTLAALAGA
361PLPNVTLDGF DLSPLLLGTG KSPRQSLFFY PSYPDEVRGV FAVRTGKYKA HFFTQGSAHS
421DTTADPACHA SSSLTAHEPP LLYDLSKDPG ENYNLLGGVA GATPEVLQAL KQLQLLKAQL
481DAAVTFGPSQ VARGEDPALQ ICCHPGCTPR PACCHCPDPH A

521 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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