CD38 Antibody (clone ABT-CD38)
Catalog Number: LS-C744468
4 sizes / from $274.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Cynomolgus CD38 Protein (Recombinant 6His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$328.00each
Catalog Number: LS-G137893-10
Catalog Number: LS-G137893
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- Description
- CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ADP-ribosyl cyclase 1 | CD38 antigen (p45) | CD38 antigen | Cyclic ADP-ribose hydrolase 1 | T10 | CADPr hydrolase 1 | CD38 | CD38 molecule | NAD(+) nucleosidase
- Origin Species
- Cynomolgus Monkey
- NCBI GenBank
- NM_001775
- SwissProt
- P28907
Protein
- Expression System
- Other
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1LPRWRQQWSG SGTTSRFPET VLARCVKYTE VHPEMRHVDC QSVWDAFKGA FISKYPCNIT61EEDYQPLVKL GTQTVPCNKT LLWSRIKDLA HQFTQVQRDM FTLEDMLLGY LADDLTWCGE121FNTFEINYQS CPDWRKDCSN NPVSVFWKTV SRRFAETACG VVHVMLNGSR SKIFDKNSTF181GSVEVHNLQP EKVQALEAWV IHGGREDSRD LCQDPTIKEL ESIISKRNIR FFCKNIYRPD241KFLQCVKNPE DSSCLSGIVD HHHHHH
266 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in 20 mM Tris, pH 8.0, 150 mM NaCl
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
