LSBio
Rat IL18 Protein (Recombinant)

Rat IL18 Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Lyophilized
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$302.00each
Catalog Number: LS-G27121-10

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Overview

Description
Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells.Recombinant rat Interleukin-18 (rrIL-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 159 amino acids. A fully biologically active molecule, rrIL-18 has a molecular mass of 18.4 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
IGIF | IL-1g | Interleukin-18 | IFN-gamma-inducing factor | IL-1 gamma | IL-18 | IL18 | Iboctadekin | IL1F4 | Interleukin-1 gamma
Origin Species
Rat
NCBI GenBank
NM_001562|NP_001553.1
SwissProt
Q14116

Protein

Expression System
Escherichia coli (Prokaryotic)
Molecular Weight
18.4 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1MHFGRLHCTT AVIRSINDQV LFVDKRNPPV FEDMPDIDRT ANESQTRLII YMYKDSEVRG
61LAVTLSVKDG RMSTLSCKNK IISFEEMNPP ENIDDIKSDL IFFQKRVPGH NKMEFESSLY
121EGHFLACQKE DDAFKLVLKR KDENGDKSVM FTLTNLHQS

159 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from 50 mM Tris-HCl, pH 8.0, 0.5 M NaCl
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.