LSBio
Rat IL-1B / IL-1 Beta Protein (Recombinant)

Rat IL-1B / IL-1 Beta Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Lyophilized
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$302.00each
Catalog Number: LS-G27097-10

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Overview

Description
Interleukin-1 Beta (IL-1 Beta) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.Recombinant rat Interleukin-1 Beta (rat IL-1 Beta) produced in E. coli is a single non-glycosylated polypeptide chain containing 152 amino acids. A fully biologically active molecule, recombinant rat IL-1 Beta protein has a molecular mass of 17.3kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
IL-1B | IL1B | IL-1 beta | IL1-BETA | Preinterleukin 1 beta | Pro-interleukin-1-beta | Catabolin | IL-1 | IL1F2 | Interleukin 1 | beta | Interleukin-1 beta
Origin Species
Rat
NCBI GenBank
NM_000576|NP_000567.1
SwissProt
P01584

Protein

Expression System
Escherichia coli (Prokaryotic)
Molecular Weight
17.3 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1VPIRQLHCRL RDEQQKCLVL SDPCELKALH LNGQNISQQV VFSMSFVQGE TSNDKIPVAL
61GLKGLNLYLS CVMKDGTPTL QLESVDPKQY PKKKMEKRFV FNKIEVKTKV EFESAQFPNW
121YISTSQAEHR PVFLGNSNGR DIVDFTMEPV SS

152 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.