TNFSF13 / APRIL Antibody
Catalog Number: LS-C192499
2 sizes / from $364.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Mouse TNFSF13 / APRIL Protein (Recombinant Fc, N-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$283.00each
Catalog Number: LS-G137854-10
Catalog Number: LS-G137854
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- Description
- Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- APRIL | CD256 | CD256 antigen | TALL-2 | TALL2 | ZTNF2 | TNF-related death ligand 1 | TNFSF13 | TRDL-1 | UNQ383/PRO715
- Origin Species
- Mouse
- NCBI GenBank
- NM_003808
- SwissProt
- O75888
Protein
- Expression System
- Other
- Fusion Tag
- Human IgG1 Fc Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1GSGSDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN61WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI121SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP181VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KIEGRAVLTQ241KHKKKHSVLH LVPVNITSKD SDVTEVMWQP VLRRGRGLEA QGDIVRVWDT GIYLLYSQVL301FHDVTFTMGQ VVSREGQGRR ETLFRCIRSM PSDPDRAYNS CYSAGVFHLH QGDIITVKIP361RANAKLSLSP HGTFLGFVKL
380 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
