LSBio
Mouse TGFB1 / TGF Beta 1 Protein (Recombinant His)

Mouse TGFB1 / TGF Beta 1 Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all TGFB1 antibodies →
$282.00each
Catalog Number: LS-G3147-10

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Overview

Description
Members of the Transforming growth factor beta (TGFB) family of cytokines are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. TGFB1 is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. Recombinant mouse TGFB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CED | DPD1 | Diaphyseal dysplasia 1 | LAP | Latency-associated peptide | TGF Beta | TGFbeta | TGF-beta 1 protein | TGF-beta-1 | TGFB | TGFB1
Origin Species
Mouse
NCBI GenBank
NM_000660|NP_000651.3
SwissProt
P01137

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
1279-390aa| MGSSHHHHHH SSGLVPRGSH MGSALDTNYC FSSTEKNCCV RQLYIDFRKD
61LGWKWIHEPK GYHANFCLGP CPYIWSLDTQ YSKVLALYNQ HNPGASASPC CVPQALEPLP
121IVYYVGRKPK VEQLSNMIVR SCKCS

145 aa

Format

Purity
>85%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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