LSBio
Mouse IFN Gamma / Interferon Gamma Protein (Recombinant)

Mouse IFN Gamma / Interferon Gamma Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Lyophilized
See all IFNG antibodies →
$259.00each
Catalog Number: LS-G27044-20

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Overview

Description
Sharing 41% sequence identity with human Interferon gamma (hIFN--gamma), mouse IFN gamma (mIFN--gamma) is a macrophage-activating factor. The active form of IFN--gamma is an antiparallel dimer that sets off IFN--gamma/JAK/STAT pathway. IFN--gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN--gamma-induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN--gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers.Recombinant mouse IFN gamma (rmIFN-gamma) produced in E. coli is a non-glycosylated polypeptide chain of 134 amino acids. A fully biologically active molecule, rmIFN--gamma has a molecular mass of 15 kDa analyzed by reducing SDS-PAGE and is obtained by refolding and chromatographic techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
IFG | Immune interferon | IFI | Interferon gamma | IFN-gamma | IFNG | Interferon | gamma | IFNY
Origin Species
Mouse
NCBI GenBank
NM_000619|NP_000610.2
SwissProt
P01579

Protein

Expression System
Escherichia coli (Prokaryotic)
Molecular Weight
15 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL
61KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL
121LPESSLRKRK RSRC

134 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.