FGF23 Antibody (clone FGF23/638)
Catalog Number: LS-C357883
2 sizes / from $379.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Functional Assay, Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Mouse FGF23 Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$274.00each
Catalog Number: LS-G133827-5
Catalog Number: LS-G133827
For bulk orders or custom formulations:
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- Description
- The FGF family plays a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant Murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ADHR | Fibroblast growth factor 23 | FGF-23 | FGF23 | HYPF | Phosphatonin | PHPTC | HPDR2
- Origin Species
- Mouse
- NCBI GenBank
- NM_020638
- SwissProt
- Q9GZV9
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- 25.5 kda
- Protein Type
- Recombinant
- Amino Acid Sequence
1aa 25-251| MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL61MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH121YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL181KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV
238 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Lyophilized
- Formulation
- Lyophilized
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Store at -20°C. Protect from moisture.
