BTC / Betacellulin Antibody
Catalog Number: LS-C335257
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Mouse BTC / Betacellulin Protein (Recombinant)
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| Expression System | Human Embryonic Kidney 293 |
| Format: | Lyophilized |
$268.00each
Catalog Number: LS-G27222-10
Catalog Number: LS-G27222
For bulk orders or custom formulations:
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- Description
- Betacellulin, also known as BTC, belongs to the EGF family of growth factors. It is expressed in many tissues, such as kidney, pancreas and small intestine. Betacellulin is initially synthesized as a membrane-bound precursor containing multiple EGF-like domains in its extracellular region, and is released from the membrane by proteolytic cleavage. BTC is the ligand for EGFR/ErbB receptor tyrosine kinases, and plays a role in cell growth and differentiation. BTC has been reported to promote beta cell growth and differentiation in the pancreas. Pancreas-specific expression of this gene may induce islet neogenesis and remediate hyperglycemia in type I diabetes.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- BTC | Betacellulin | Probetacellulin
- Origin Species
- Mouse
- NCBI GenBank
- NM_001729|NP_001720.1
- SwissProt
- P35070
Protein
- Expression System
- Human Embryonic Kidney 293
- Molecular Weight
- 19-24 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP61SCICEKGYFG ARCERVDLFY
80 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
