LSBio
LF / LTF / Lactoferrin Protein (Native)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LF / LTF / Lactoferrin Protein (Native)

Expression SystemHuman Embryonic Kidney 293
Format:Liquid
See all LTF antibodies →
$568.00each
Catalog Number: LS-G132072-1

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Overview

Description
Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
Category
Proteins & Peptides > Proteins > Native Proteins
Alternative Names
GIG12 | Growth-inhibiting protein 12 | HLF2 | Lactotransferrin | LTF | Lactoferrin | LF | Neutrophil lactoferrin | Talalactoferrin
NCBI GenBank
NM_002343
SwissProt
P02788

Protein

Expression System
Human Embryonic Kidney 293
Protein Type
Native

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
10.9 mg/mL
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

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