VEGFA / VEGF Antibody (clone VEGF/1063)
Catalog Number: LS-C391126
2 sizes / from $379.00
Antibody: Mouse Monoclonal
Applications: Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity: Human
Format: Liquid
Biological Activity VEGF-A165, Human stimulates cell proliferation of HUVEC cells. The ED 50 for this effect is typically 1-5 ng/mL.
Human VEGF 165 Protein (Recombinant)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$302.00each
Catalog Number: LS-G27034-10
Catalog Number: LS-G27034
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- Description
- Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human Vascular Endothelial Growth Factor A165 (rhVEGF-A165) produced in Pichia pastoris is a disulfide-linked homodimer containing two polypeptide chains of 165 amino acids each. A fully biologically active molecule, rhVEGF-A165 has a molecular mass of 38.2kDa analyzed by non-reducing SDS-PAGE and is obtained by chromatographic techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Origin Species
- Human
Protein
- Expression System
- Other
- Molecular Weight
- 38.2 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC61CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC121SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
165 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.5 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from 25mM HEPES, pH 7.0, 150mM NaCl
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 1 year. Upon reconstitution, store at 4°c for up to 4 weeks or at -20°c for up to 6 months.
