LSBio
Human TNFRSF17 / BCMA Protein (Recombinant Fc, C-terminus)

Human TNFRSF17 / BCMA Protein (Recombinant Fc, C-terminus)

Expression SystemOther
Format:Lyophilized
See all TNFRSF17 antibodies →
$275.00each
Catalog Number: LS-G137858-10

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Overview

Description
B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
B cell maturation antigen | BCMA | CD269 antigen | B-cell maturation factor | B-cell maturation protein | BCM | TNFRSF17 | CD269
Origin Species
Hu
NCBI GenBank
NM_001192
SwissProt
Q02223

Protein

Expression System
Other
Fusion Tag
hFc
Protein Type
Recombinant
Amino Acid Sequence
1MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNADIEGRM
61DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK
121FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK
181TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT
241PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK

293 aa

Format

Purity
>95%
Conjugate/Label
Unconj
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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