TMEM173 / STING Antibody
Catalog Number: LS-C332665
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse
Format: Liquid
Human TMEM173 / STING Protein (Recombinant 6His-SUMO, N-terminus)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$294.00each
Catalog Number: LS-G137900-10
Catalog Number: LS-G137900
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- Description
- Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ERIS | MITA | HSTING | Transmembrane protein 173 | TMEM173 | HMITA | Mediator of IRF3 activation | MPYS | NET23 | STING
- Origin Species
- Human
- SwissProt
- Q86WV6
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag, Small Ubiquitin-like Modifier Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1MGHHHHHHGS LQDSEVNQEA KPEVKPEVKP ETHINLKVSD GSSEIFFKIK KTTPLRRLME61AFAKRQGKEM DSLRFLYDGI RIQADQAPED LDMEDNDIIE AHREQIGGVA HGLAWSYYIG121YLRLILPELQ ARIRTYNQHY NNLLRGAVSQ RLYILLPLDC GVPDNLSMAD PNIRFLDKLP181QQTGDHAGIK DRVYSNSIYE LLENGQRAGT CVLEYATPLQ TLFAMSQYSQ AGFSREDRLE241QAKLFCRTLE DILADAPESQ NNCRLIAYQE PADDSSFSLS QEVLRHLRQE EKEEV
295 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Store at < -20°C for up to 6 months. Avoid freeze-thaw cycles.
