TLR8 Antibody
Catalog Number: LS-C490591-100
100 µg / $587.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human, Rat
Format: Lyophilized
Human TLR8 Protein (Recombinant 6His, N-terminus)
ProteinLSBio Guarantee
| Expression System | Yeast |
| Format: | Liquid |
$343.00each
Catalog Number: LS-G23167-20
Catalog Number: LS-G23167
For bulk orders or custom formulations:
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- Description
- TLR8 Protein LS-G23167 is a Recombinant Human TLR8 produced in Yeast aa 27-827 with 6His, N-terminus tag(s). For Research Use Only
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CD288 | TLR8 | Toll-like receptor 8 | CD288 antigen
- Origin Species
- Human
- NCBI GenBank
- NM_138636|NP_619542.1
- SwissProt
- Q9NR97
Protein
- Expression System
- Yeast
- Fusion Tag
- Hexahistidine Tag
- Molecular Weight
- 93.4 kD
- Protein Type
- Recombinant
- Amino Acid Sequence
1aa 27-827| EENFSRSYPC DEKKQNDSVI AECSNRRLQE VPQTVGKYVT ELDLSDNFIT61HITNESFQGL QNLTKINLNH NPNVQHQNGN PGIQSNGLNI TDGAFLNLKN LRELLLEDNQ121LPQIPSGLPE SLTELSLIQN NIYNITKEGI SRLINLKNLY LAWNCYFNKV CEKTNIEDGV181FETLTNLELL SLSFNSLSHV PPKLPSSLRK LFLSNTQIKY ISEEDFKGLI NLTLLDLSGN241CPRCFNAPFP CVPCDGGASI NIDRFAFQNL TQLRYLNLSS TSLRKINAAW FKNMPHLKVL301DLEFNYLVGE IASGAFLTML PRLEILDLSF NYIKGSYPQH INISRNFSKL LSLRALHLRG361YVFQELREDD FQPLMQLPNL STINLGINFI KQIDFKLFQN FSNLEIIYLS ENRISPLVKD421TRQSYANSSS FQRHIRKRRS TDFEFDPHSN FYHFTRPLIK PQCAAYGKAL DLSLNSIFFI481GPNQFENLPD IACLNLSANS NAQVLSGTEF SAIPHVKYLD LTNNRLDFDN ASALTELSDL541EVLDLSYNSH YFRIAGVTHH LEFIQNFTNL KVLNLSHNNI YTLTDKYNLE SKSLVELVFS601GNRLDILWND DDNRYISIFK GLKNLTRLDL SLNRLKHIPN EAFLNLPASL TELHINDNML661KFFNWTLLQQ FPRLELLDLR GNKLLFLTDS LSDFTSSLRT LLLSHNRISH LPSGFLSEVS721SLKHLDLSSN LLKTINKSAL ETKTTTKLSM LELHGNPFEC TCDIGDFRRW MDEHLNVKIP781RLVDVICASP GDQRGKSIVS LELTTCVSDV T
811 aa
Format
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- Tris, 50% Glycerol
- Concentration
- 0.5 mg/mL
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. Paul Dembny, Andrew G Newman, Manvendra Singh, Michael Hinz, Michal Szczepek, Christina Krüger, Robert Adalbert, Omar Dzaye, Thorsten Trimbuch, Thomas Wallach, Gunnar Kleinau, Katja Derkow, Bernhard C Richard, Carola Schipke, Claus Scheidereit, Harald Stachelscheid, Douglas Golenbock, Oliver Peters, Michael Coleman, Frank L Heppner, Patrick Scheerer, Victor Tarabykin, Klemens Ruprecht, Zsuzsanna Izsvák, Jens Mayer, Seija Lehnardt. JCI insight. 2020 April;5.
PubMed: 32271161 · PMC: PMC7205273
MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration. Thomas Wallach , Zoé J Mossmann , Michal Szczepek, Max Wetzel, Rui Machado, Martin Raden, Milad Miladi, Gunnar Kleinau, Christina Krüger, Paul Dembny, Drew Adler, Yuanyuan Zhai, Victor Kumbol, Omar Dzaye, Jutta Schüler, Matthias Futschik, Rolf Backofen, Patrick Scheerer, Seija Lehnardt. Molecular neurodegeneration. 2021 November;16:80.
PubMed: 34838071 · PMC: PMC8626928
