TCEB2 / Elongin B Antibody
Catalog Number: LS-C137534-100
100 µL (1 mg/mL) / $454.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Liquid
Human TCEB2 / Elongin B Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$250.00each
Catalog Number: LS-G3397-20
Catalog Number: LS-G3397
For bulk orders or custom formulations:
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- Description
- Elongin B , also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant TCEB2 was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ELOB | Elongin 18 kDa subunit | Elongin-B | Elongin | 18-kD subunit | SIII | SIII p18 | TCEB2
- Origin Species
- Human
- NCBI GenBank
- NM_007108|NP_009039.1
- SwissProt
- Q15370
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Protein Type
- Recombinant
- Amino Acid Sequence
11-118aa|MD VFLMIRRHKT TIFTDAKESS TVFELKRIVE GILKRPPDEQ RLYKDDQLLD61DGKTLGECGF TSQTARPQAP ATVGLAFRAD DTFEALCIEP FSSPPELPDV MKPQDSGSSA121NEQAVQ
126 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl buffer (pH 8.0) containing 1mMDTT, 0.1mM PMSF, 20% glycerol.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
