SPOP Antibody
Catalog Number: LS-C109401-100
100 µL (0.1 mg/mL) / $459.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human
Format: Liquid
Human SPOP Protein (Recombinant His)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$282.00each
Catalog Number: LS-G1229-10
Catalog Number: LS-G1229
For bulk orders or custom formulations:
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- Description
- SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. This protein inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. Through an interaction with CuL-3, SPOP is involved in ubiquitinylation and protein degradation. Recombinant human SPOP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- BTBD32 | HIB homolog 1 | TEF2 | Roadkill homolog 1 | Speckle-type POZ protein | SPOP
- Origin Species
- Human
- NCBI GenBank
- NP_003554.1
- SwissProt
- O43791
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
11-374aa|MG SSHHHHHHSS GLVPRGSHMS RVPSPPPPAE MSSGPVAESW CYTQIKVVKF61SYMWTINNFS FCREEMGEVI KSSTFSSGAN DKLKWCLRVN PKGLDEESKD YLSLYLLLVS121CPKSEVRAKF KFSILNAKGE ETKAMESQRA YRFVQGKDWG FKKFIRRDFL LDEANGLLPD181DKLTLFCEVS VVQDSVNISG QNTMNMVKVP ECRLADELGG LWENSRFTDC CLCVAGQEFQ241AHKAILAARS PVFSAMFEHE MEESKKNRVE INDVEPEVFK EMMCFIYTGK APNLDKMADD301LLAAADKYAL ERLKVMCEDA LCSNLSVENA AEILILADLH SADQLKTQAV DFINYHASDV361LETSGWKSMV VSHPHLVAEA YRSLASAQCP FLGPPRKRLK QS
402 aa
Format
- Purity
- >90%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 0.2M NaCl, 2mM EDTA.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
