SET / TAF-I Antibody
Catalog Number: LS-C341968
2 sizes / from $364.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Human SET / TAF-I Protein (Recombinant His)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$267.00each
Catalog Number: LS-G2411-20
Catalog Number: LS-G2411
For bulk orders or custom formulations:
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- Description
- SET inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. Recombinant human SET protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- 2PP2A | HLA-DR-associated protein II | I-2PP2A | SET | TAF-IBETA | SET nuclear oncogene | TAF-I | Template-activating factor I | I2PP2A | IGAAD | IPP2A2 | PHAPII | Protein SET
- Origin Species
- Human
- NCBI GenBank
- NM_003011|NP_003002.2
- SwissProt
- Q01105
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
11-290aa|MG SSHHHHHHSS GLVPRGSHMG SMAPKRQSPL PPQKKKPRPP PALGPEETSA61SAGLPKKGEK EQQEAIEHID EVQNEIDRLN EQASEEILKV EQKYNKLRQP FFQKRSELIA121KIPNFWVTTF VNHPQVSALL GEEDEEALHY LTRVEVTEFE DIKSGYRIDF YFDENPYFEN181KVLSKEFHLN ESGDPSSKST EIKWKSGKDL TKRSSQTQNK ASRKRQHEEP ESFFTWFTDH241SDAGADELGE VIKDDIWPNP LQYYLVPDMD DEEGEGEEDD DDDEEEEGLE DIDEEGDEDE301GEEDEDDDEG EEGEEDEGED D
321 aa
Format
- Purity
- >90%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl, pH 8.0, 0.15 M NaCl, 1 mM DTT, 20% Glycerol
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
