LSBio
Human SEMA3A / Semaphorin 3A Protein (Recombinant 6His-Flag, C-terminus)

Human SEMA3A / Semaphorin 3A Protein (Recombinant 6His-Flag, C-terminus)

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Expression SystemOther
Format:Lyophilized
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$294.00each
Catalog Number: LS-G137909-10

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Overview

Description
emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Collapsin 1 | Coll-1 | Hsema-III | Hsema-I | Sema III | SEMAIII | SEMAL | Semaphorin III | Semaphorin-3A | Semaphorin-iii (hsema-i) | SemD | SEMA1 | SEMA3A | Semaphorin D | COLL1 | SEMAD | Semaphorin 3A | Semaphorin L | SEM3A
Origin Species
Hu
NCBI GenBank
NM_006080
SwissProt
Q14563

Protein

Expression System
Other
Fusion Tag
6×His, FLAG
Protein Type
Recombinant
Amino Acid Sequence
1aa26-546|G SGSHHHHHHD YKDDDDKKNN VPRLKLSYKE MLESNNVITF NGLANSSSYH
61TFLLDEERSR LYVGAKDHIF SFDLVNIKDF QKIVWPVSYT RRDECKWAGK DILKECANFI
121KVLKAYNQTH LYACGTGAFH PICTYIEIGH HPEDNIFKLE NSHFENGRGK SPYDPKLLTA
181SLLIDGELYS GTAADFMGRD FAIFRTLGHH HPIRTEQHDS RWLNDPKFIS AHLISESDNP
241EDDKVYFFFR ENAIDGEHSG KATHARIGQI CKNDFGGHRS LVNKWTTFLK ARLICSVPGP
301NGIDTHFDEL QDVFLMNFKD PKNPVVYGVF TTSSNIFKGS AVCMYSMSDV RRVFLGPYAH
361RDGPNYQWVP YQGRVPYPRP GTCPSKTFGG FDSTKDLPDD VITFARSHPA MYNPVFPMNN
421RPIVIKTDVN YQFTQIVVDR VDAEDGQYDV MFIGTDVGTV LKVVSIPKET WYDLEEVLLE
481EMTVFREPTA ISAMELSTKQ QQLYIGSTAG VAQLPLHRCD IYGKACAECC LARDPYCAWD
541GSACSRYF

548 aa

Format

Purity
>90%
Conjugate/Label
Unconj
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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