LSBio
Human RPL12 / Ribosomal Protein L12 (Recombinant)

Human RPL12 / Ribosomal Protein L12 (Recombinant)

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Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
See all RPL12 antibodies →
$274.00each
Catalog Number: LS-G133799-2

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Overview

Description
IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-? production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-?-producing Th1 cells. PeproTech's Recombinant Human IL-12 p70, derived from HEK293 cells, is a heterodimeric glycoprotein consisting of disulfide-linked p35 and p40 subunits (503 total amino acid residues). The calculated molecular weight of Human IL-12 p70 is 57.2 kDa; however, due to glycosylation, it migrates at an apparent molecular weight of 65-70 kDa based on SDS-PAGE gel, under non-reducing conditions.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
60S ribosomal protein L12 | L12 | RPL12 | Ribosomal protein L12
Origin Species
Human
NCBI GenBank
NM_000976
SwissProt
P30050

Protein

Expression System
Human Embryonic Kidney 293
Molecular Weight
57.2 kDa or 65-70 kDa
Protein Type
Recombinant
Amino Acid Sequence
1(p35-Subun it)RNLPVAT PDPGMFPCLH HSQNLLRAVS NMLQKARQTL EFYPCTSEEI
61DHEDITKDKT STVEACLPLE LTKNESCLNS RETSFITNGS CLASRKTSFM MALCLSSIYE
121DLKMYQVEFK TMNAKLLMDP KRQIFLDQNM LAVIDELMQA LNFNSETVPQ KSSLEEPDFY
181KTKIKLCILL HAFRIRAVTI DRVMSYLNAS (p40-Subun it)IWELKKD VYVVELDWYP
241DAPGEMVVLT CDTPEEDGIT WTLDQSSEVL GSGKTLTIQV KEFGDAGQYT CHKGGEVLSH
301SLLLLHKKED GIWSTDILKD QKEPKNKTFL RCEAKNYSGR FTCWWLTTIS TDLTFSVKSS
361RGSSDPQGVT CGAATLSAER VRGDNKEYEY SVECQEDSAC PAAEESLPIE VMVDAVHKLK
421YENYTSSFFI RDIIKPDPPK NLQLKPLKNS RQVEVSWEYP DTWSTPHSYF SLTFCVQVQG
481KSKREKKDRV FTDKTSATVI CRKNASISVR AQDRYYSSSW SEWASVPCS

529 aa

Format

Purity
>98%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Lyophilized
Formulation
Lyophilized
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Store at -20°C. Protect from moisture.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.