LSBio
Human RASSF1 / RASSF1A Protein (Recombinant His)

Human RASSF1 / RASSF1A Protein (Recombinant His)

Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$267.00each
Catalog Number: LS-G2033-20

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Overview

Description
RASSF1A is similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. This protein required for death receptor-dependent apoptosis. Recombinant human RASSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
123F2 | RASSF1A | RDA32 | Tumor suppressor protein RDA32 | NORE2A | RASSF1 | WUGSC:H_LUCA12.5 | REH3P21
Origin Species
Human
SwissProt
Q9NS23

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
11-340aa|MR GSHHHHHHGM ASMTGGQQMG RDLYDDDDKD RWGSMSGEPE LIELRELAPA
61GRAGKGRTRL ERANALRIAR GTACNPTRQL VPGRGHRFQP AGPATHTWCD LCGDFIWGVV
121RKGLQCAHCK FTCHYRCRAL VCLDCCGPRD LGWEPAVERD TNVDEPVEWE TPDLSQAEIE
181QKIKEYNAQI NSNLFMSLNK DGSYTGFIKV QLKLVRPVSV PSSKKPPSLQ DARRGPGRGT
241SVRRRTSFYL PKDAVKHLHV LSRTRAREVI EALLRKFLVV DDPRKFALFE RAERHGQVYL
301RKLLDDEQPL RLRLLAGPSD KALSFVLKEN DSGEVNWDAF SMPELHNFLR ILQREEEEHL
361RQILQKYSYC RQKIQEALHA CPLG

384 aa

Format

Purity
>85%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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