LSBio
Human PIN4 Protein (Recombinant His)

Human PIN4 Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$282.00each
Catalog Number: LS-G1221-20

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Overview

Description
PIN4, also known as Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, is peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and is essential for cell cycle regulation. There are two different isoforms which are PAR14 and PAR17. PIN4/PAR17 was imported into mitochondria in a time and membrane potential-dependent manner, where it reached the mitochondrial matrix. Moreover, Pin4 protein was shown to bind to double-stranded DNA under physiological salt conditions. Recombinant human PIN4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
EPVH | Eukaryotic parvulin homolog | HEPVH | HPar17 | Parvulin-17 | Parvulin-14 | PIN4 | PPIase Pin4 | Rotamase Pin4 | PAR14 | HPar14 | PAR17
Origin Species
Human
NCBI GenBank
NM_006223|NP_006214.2
SwissProt
Q9Y237

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
11-156aa|MG SSHHHHHHSS GLVPRGSHMP MAGLLKGLVR QLERFSVQQQ ASKMPPKGKS
61GSGKAGKGGA ASGSDSADKK AQGPKGGGNA VKVRHILCEK HGKIMEAMEK LKSGMRFNEV
121AAQYSEDKAR QGGDLGWMTR GSMVGPFQEA AFALPVSGMD KPVFTDPPVK TKFGYHIIMV
181EGRK

184 aa

Format

Purity
>85%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M NaCl, 10% glycerol.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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