LSBio
Human MAPT / Tau Protein (Recombinant His)

Human MAPT / Tau Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$264.00each
Catalog Number: LS-G1047-10

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Overview

Description
Tau, also known as microtubule-associated protein tau (MAPT), is a protein that stabilizes microtubules. It is abundant in neurons in the central nervous system and is less common elsewhere. When this protein is defective, and no longer stabilizes microtubules properly, it can result in dementias, such as Alzheimer's disease. Recombinant human Tau protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Gene Name
MAPT
Alternative Names
FTDP-17 | MAPT | MSTD | Neurofibrillary tangle protein | PHF-tau | MTBT2 | PPND | DDPAC | MAPTL | MTBT1 | Paired helical filament-tau | TAU
Origin Species
Human
UniProt Number
P10636
NCBI GenBank
NM_016835
SwissProt
P10636

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
1aa1-383|MG SSHHHHHHSS GLVPRGSHMA EPRQEFEVME DHAGTYGLGD RKDQGGYTMH
61QDQEGDTDAG LKAEEAGIGD TPSLEDEAAG HVTQARMVSK SKDGTGSDDK KAKGADGKTK
121IATPRGAAPP GQKGQANATR IPAKTPPAPK TPPSSGEPPK SGDRSGYSSP GSPGTPGSRS
181RTPSLPTPPT REPKKVAVVR TPPKSPSSAK SRLQTAPVPM PDLKNVKSKI GSTENLKHQP
241GGGKVQIINK KLDLSNVQSK CGSKDNIKHV PGGGSVQIVY KPVDLSKVTS KCGSLGNIHH
301KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA
361EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L

411 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.