LSBio
Human KRT5 / CK5 / Cytokeratin 5 Protein (Recombinant His)

Human KRT5 / CK5 / Cytokeratin 5 Protein (Recombinant His)

Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all KRT5 antibodies →
$267.00each
Catalog Number: LS-G2854-20

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Overview

Description
KRT5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. Recombinant human KRT5 protein, fused to His-tag at N-terminus, was expressed in E.coli
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
58 kd cytokeratin | 58 kDa cytokeratin | CK5 | CK-5 | Cytokeratin-5 | DDD | EBS2 | Keratin 5 | KRT5A | KRT5 | Type-II keratin Kb5 | Cytokeratin 5 | K5 | Keratin-5
Origin Species
Human
SwissProt
P13647

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
11-590aa|MG SSHHHHHHSS GLVPRGSHMG SMSRQSSVSF RSGGSRSFST ASAITPSVSR
61TSFTSVSRSG GGGGGGFGRV SLAGACGVGG YGSRSLYNLG GSKRISISTS GGSFRNRFGA
121GAGGGYGFGG GAGSGFGFGG GAGGGFGLGG GAGFGGGFGG PGFPVCPPGG IQEVTVNQSL
181LTPLNLQIDP SIQRVRTEER EQIKTLNNKF ASFIDKVRFL EQQNKVLDTK WTLLQEQGTK
241TVRQNLEPLF EQYINNLRRQ LDSIVGERGR LDSELRNMQD LVEDFKNKYE DEINKRTTAE
301NEFVMLKKDV DAAYMNKVEL EAKVDALMDE INFMKMFFDA ELSQMQTHVS DTSVVLSMDN
361NRNLDLDSII AEVKAQYEEI ANRSRTEAES WYQTKYEELQ QTAGRHGDDL RNTKHEISEM
421NRMIQRLRAE IDNVKKQCAN LQNAIADAEQ RGELALKDAR NKLAELEEAL QKAKQDMARL
481LREYQELMNT KLALDVEIAT YRKLLEGEEC RLSGEGVGPV NISVVTSSVS SGYGSGSGYG
541GGLGGGLGGG LGGGLAGGGS GSYYSSSSGG VGLSGGLSVG GSGFSASSGR GLGVGFGSGG
601GSSSSVKFVS TTSSSRKSFK S

621 aa

Format

Purity
>85%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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