LSBio
Human KLK2 / Kallikrein 2 Protein (Recombinant His)

Human KLK2 / Kallikrein 2 Protein (Recombinant His)

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Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$267.00each
Catalog Number: LS-G2393-20

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Overview

Description
KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. KLK2 is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. Recombinant human KLK2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Glandular kallikrein 2 | Glandular kallikrein-1 | HGK-1 | Kallikrein 2 | prostatic | Kallikrein-2 | Kallikrein-related peptidase 2 | KLK2 | KLK2A2 | Tissue kallikrein-2
Origin Species
Human
NCBI GenBank
NM_005551|NP_005542.1
SwissProt
P20151

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
125-261aa|M GSSHHHHHHS SGLVPRGSHM GSIVGGWECE KHSQPWQVAV YSHGWAHCGG
61VLVHPQWVLT AAHCLKKNSQ VWLGRHNLFE PEDTGQRVPV SHSFPHPLYN MSLLKHQSLR
121PDEDSSHDLM LLRLSEPAKI TDVVKVLGLP TQEPALGTTC YASGWGSIEP EEFLRPRSLQ
181CVSLHLLSND MCARAYSEKV TEFMLCAGLW TGGKDTCGGD SGGPLVCNGV LQGITSWGPE
241PCALPEKPAV YTKVVHYRKW IKDTIAANP

269 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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