Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.

Human KDR / VEGFR2 / FLK1 Protein (Recombinant Human IgG Fc, C-terminus)

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Expression System	Human Embryonic Kidney 293
Format:	Lyophilized

$490.00each

Catalog Number: LS-G47161-100

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Overview

Description: KDR / VEGFR2 / FLK1 Protein LS-G47161 is a Recombinant Human KDR / VEGFR2 / FLK1 produced in HEK 293 Cells Met1-Glu764 with Human IgG Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Category: Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names: CD309 | Fetal liver kinase 1 | Fetal liver kinase-1 | KDR | FLK-1 | FLK1 | Kinase insert domain receptor | Quek1 | VEGFR | VEGFR2 | Soluble VEGFR2 | VEGF receptor 2 | VEGFR-2 | CD309 antigen | VEGF-R2
Origin Species: Human
NCBI GenBank: NM_002253
SwissProt: P35968

Protein

Expression System: Human Embryonic Kidney 293
Fusion Tag: Human IgG1 Fc Tag
Molecular Weight: The recombinant human VEGFR2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 979 amino acids and predicts a molecular mass of 109 kDa. The apparent molecular mass of rh VEGFR2/Fc monomer is approximatly 150-160 in SDS-PAGE under reducing conditions.
Protein Type: Recombinant
Amino Acid Sequence

Format

Purity: >90%
Conjugate/Label: Unconjugated
Endotoxin Level: < 1.0 EU/µg
Format: Lyophilized
Formulation: Lyophilized from sterile PBS, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween80.
Purity Measurement Method: SDS-PAGE (Coomassie Stain)