Overview

Description

Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

Category

Proteins & Peptides > Proteins > Recombinant Proteins

Alternative Names

Cytokine P40 | IL-9 | Interleukin-9 | HP40 | IL9 | p40 cytokine | Interleukin 9 | T-cell growth factor P40 | p40

Origin Species

Human

NCBI GenBank

NM_000590|NP_000581.1

SwissProt

P15248