IL6 / Interleukin 6 Antibody
Catalog Number: LS-C104444-500
500 µg / $333.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Lyophilized
Biological Activity IL-6, Human stimulates cell proliferation of 7TD1 cells. The ED 50 for this effect is less than 0.1ng/mL.
Human IL6 / Interleukin 6 Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$284.00each
Catalog Number: LS-G27126-10
Catalog Number: LS-G27126
For bulk orders or custom formulations:
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- Description
- Interleukin-6 (IL-6, also known as IFN-Beta2) is a pleiotropic cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 is secreted by T cells and macrophages to stimulate immune response. IL-6 is responsible for stimulating acute phase protein synthesis, as well as the production of neutrophils in the bone marrow. It supports the growth of B cells and is antagonistic to regulatory T cells.Recombinant human Interleukin-6 (rhIL-6) produced in E. coli is a single non-glycosylated polypeptide chain containing 185 amino acids. A fully biologically active molecule, rhIL-6 has a molecular mass of 20.9 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- B-cell stimulatory factor 2 | BSF-2 | BSF2 | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IL6 | Interleukin-6 | Interleukin BSF-2 | IFNB2 | B-cell differentiation factor | CDF | HSF | IL-6
- Origin Species
- Human
- NCBI GenBank
- NM_000600|NP_000591.1
- SwissProt
- P05231
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- 20.9 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE61NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST121KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR181ALRQM
185 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.
