Binding of IL-2 Superkine (Fc) (AG-40B-0111) to IL-2Rbeta (human) is increased >10 fold compared to IL-2 (human):Fc (human) . Methods: IL-2Rbeta (human) was coated on an ELISA plate at 1 ug/ml. After blocking and washing steps, indicated concentrations of IL-2 Superkine (Fc) or IL-2 (human):Fc (human) were added. Following incubation for 1 h at RT, the binding was detected using an anti-human Fc antibody (HRP).

Human IL2 Protein (Recombinant Human IgG2 Fc)

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Expression System	Human Embryonic Kidney 293
Format:	Lyophilized

$394.00each

Catalog Number: LS-G3948-10

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Overview

Description: The extracellular domain of human IL-2 (aa 21-153) (mutant H9 containing the mutations L80F / R81D / L85V / I 86V / I92F) is fused at the C-terminus to the Fc portion of human IgG2.
Category: Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names: Aldesleukin | IL2 | Interleukin 2 | Lymphokine | IL-2 | Interleukin-2 | TCGF | T cell growth factor | T-cell growth factor
Origin Species: Human
NCBI GenBank: NM_000586|NP_000577.2
SwissProt: P60568

Protein

Expression System: Human Embryonic Kidney 293
Fusion Tag: Other
Molecular Weight: 42kda
Protein Type: Recombinant
Amino Acid Sequence

Format

Purity: >95%
Conjugate/Label: Unconjugated
Endotoxin Level: < 0.01 EU/µg
Format: Lyophilized
Formulation: Lyophilized from PBS
Purity Measurement Method: SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions: Store lyophilized at -20°C for up to 1 year. Once reconstituted store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.