IL12RB1 / CD212 Antibody
Catalog Number: LS-C662191-100
100 µg / $480.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human
Format: Lyophilized
Human IL12RB1 / CD212 Protein (Recombinant His)
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| Expression System | Insect Cells |
| Format: | Liquid |
$267.00each
Catalog Number: LS-G3294-10
Catalog Number: LS-G3294
For bulk orders or custom formulations:
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- Description
- IL12RB1, also known as Interleukin-12 receptor subunit beta-1, is a intercellular adhesion molecule 1. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. It forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this protein and IL12RB2 was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Recombinant human IL12RB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CD212 | IL-12R subunit beta-1 | IL-12R-beta-1 | IL12R | IL12RB1 | Interleukin-12 receptor | IL-12 receptor subunit beta-1 | IL-12R-BETA1 | IL-12RB1 | CD212 antigen | IL-12 receptor beta component | IL12RB
- Origin Species
- Human
- NCBI GenBank
- NM_005535|NP_005526.1
- SwissProt
- P42701
Protein
- Expression System
- Insect Cells
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
124-545aa|C RTSECCFQDP PYPDADSGSA SGPRDLRCYR ISSDRYECSW QYEGPTAGVS61HFLRCCLSSG RCCYFAAGSA TRLQFSDQAG VSVLYTVTLW VESWARNQTE KSPEVTLQLY121NSVKYEPPLG DIKVSKLAGQ LRMEWETPDN QVGAEVQFRH RTPSSPWKLG DCGPQDDDTE181SCLCPLEMNV AQEFQLRRRQ LGSQGSSWSK WSSPVCVPPE NPPQPQVRFS VEQLGQDGRR241RLTLKEQPTQ LELPEGCQGL APGTEVTYRL QLHMLSCPCK AKATRTLHLG KMPYLSGAAY301NVAVISSNQF GPGLNQTWHI PADTHTEPVA LNISVGTNGT TMYWPARAQS MTYCIEWQPV361GQDGGLATCS LTAPQDPDPA GMATYSWSRE SGAMGQEKCY YITIFASAHP EKLTLWSTVL421STYHFGGNAS AAGTPHHVSV KNHSLDSVSV DWAPSLLSTC PGVLKEYVVR CRDEDSKQVS481EHPVQPTETQ VTLSGLRAGV AYTVQVRADT AWLRGVWSQP QRFSIEVQVS DHHHHHH
537 aa
Format
- Purity
- >90%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1.0 EU/µg
- Format
- Liquid
- Formulation
- Phosphate buffer saline (pH 7.4) containing 30% glycerol, 1mM EDTA, 0.1mM PMSF.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
