LSBio
Human IgG1 Fc Protein (Recombinant)

Human IgG1 Fc Protein (Recombinant)

Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
$451.00each
Catalog Number: LS-G4088-100

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Overview

Description
Human IgG Fc region (aa 100-330) containing the hinge sequence. Mutations were made in the CH2 domain of the Fcg2a fragment using site-directed mutagenesis to replace Glu318, Lys320, and Lys322 with Ala residues and to replace Leu235 with Glu to render the Fcg2a fragment ineffective in directing ADCC and CDC to create a Fc immunoligand.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Origin Species
Human

Protein

Expression System
Human Embryonic Kidney 293
Protein Type
Recombinant
Amino Acid Sequence
1aa 100-330 of P01857

20 aa

Format

Purity
>98%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.06 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Store lyophilized at -20°C for up to 1 year. Once reconstituted store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.