LSBio
Human IGFBP2 / IGF-BP53 Protein (Recombinant His, C-Terminal)

Human IGFBP2 / IGF-BP53 Protein (Recombinant His, C-Terminal)

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Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
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$268.00each
Catalog Number: LS-G27252-10

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Overview

Description
IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
BP2 | IGFBP-2 | IGF-binding protein 2 | IBP-2 | IGFBP2 | IBP2 | IGF-BP53
Origin Species
Human
NCBI GenBank
NM_000597|NP_000588.2
SwissProt
P18065

Protein

Expression System
Human Embryonic Kidney 293
Fusion Tag
Hexahistidine Tag
Molecular Weight
6-20 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1FRCPPCTPER LAACGPPPVA PPAAVAAVAG GARMPCAELV REPGCGCCSV CARLEGEACG
61VYTPRCGQGL RCYPHPGSEL PLQALVMGEG TCEKRRDAEY GASPEQVADN GDDHSEGGLV
121ENHVDSTMNM LGGGGSAGRK PLKSGMKELA VFREKVTEQH RQMGKGGKHH LGLEEPKKLR
181PPPARTPCQQ ELDQVLERIS TMRLPDERGP LEHLYSLHIP NCDKHGLYNL KQCKMSLNGQ
241RGECWCVNPN TGKLIQGAPT IRGDPECHLF YNEQQEARGV HTQRMQHHHH HH

292 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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