HLA-DRB1 Antibody
Catalog Number: LS-C409239
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunofluorescence, Western Blot
Reactivity: Human, Mouse
Format: Liquid
Human HLA-DRB1 Protein (Recombinant His)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$267.00each
Catalog Number: LS-G2798-20
Catalog Number: LS-G2798
For bulk orders or custom formulations:
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- Description
- HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Recombinant human HLA-DRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- DRB1 | HLA-DR1B | HLA-DRB | HLA-DRB1 | Human leucocyte antigen DRB1 | MHC class II antigen DRB1*10 | MHC class II antigen | MHC class II antigen DRB1*1 | HLA-DRB2 | Lymphocyte antigen DRB1 | SS1
- Origin Species
- Human
- NCBI GenBank
- NM_002124|NP_002115.2
- SwissProt
- P01911
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
130-227aa|M GSSHHHHHHS SGLVPRGSHM GDTRPRFLWQ PKRECHFFNG TERVRFLDRY61FYNQEESVRF DSDVGEFRAV TELGRPDAEY WNSQKDILEQ ARAAVDTYCR HNYGVVESFT121VQRRVQPKVT VYPSKTQPLQ HHNLLVCSVS GFYPGSIEVR WFLNGQEEKA GMVSTGLIQN181GDWTFQTLVM LETVPRSGEV YTCQVEHPSV TSPLTVEWRA RSESAQSK
228 aa
Format
- Purity
- >85%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
