GPNMB / Osteoactivin Antibody
Catalog Number: LS-C816456-100
100 µL / $309.00
Antibody: Rabbit Polyclonal
Applications: Immunocytochemistry, Immunofluorescence
Reactivity: Human
Format: Liquid
Human GPNMB / Osteoactivin Protein (Recombinant His)
ProteinLSBio Guarantee
| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$267.00each
Catalog Number: LS-G2501-20
Catalog Number: LS-G2501
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. The protein shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human GPNMB protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Glycoprotein nmb-like protein | HGFIN | GPNMB | Glycoprotein NMB | Osteoactivin | Transmembrane glycoprotein NMB
- Origin Species
- Human
- NCBI GenBank
- NM_002510|NP_002501.1
- SwissProt
- Q14956
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
122-474aa|M GSSHHHHHHS SGLVPRGSHM GSAKRFHDVL GNERPSAYMR EHNQLNGWSS61DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN LIFPRCQKED121ANGNIVYEKN CRNEAGLSAD PYVYNWTAWS EDSDGENGTG QSHHNVFPDG KPFPHHPGWR181RWNFIYVFHT LGQYFQKLGR CSVRVSVNTA NVTLGPQLME VTVYRRHGRA YVPIAQVKDV241YVVTDQIPVF VTMFQKNDRN SSDETFLKDL PIMFDVLIHD PSHFLNYSTI NYKWSFGDNT301GLFVSTNHTV NHTYVLNGTF SLNLTVKAAA PGPCPPPPPP PRPSKPTPSL GPAGDNPLEL361SRIPDENCQI NRYGHFQATI TIVEGILEVN IIQMTDVLMP VPWPESSLID FVVTCQGSIP421TEVCTIISDP TCEITQNTVC SPVDVDEMCL LTVRRTFNGS GTYCVNLTLG DDTSLALTST481LISVP
485 aa
Format
- Purity
- >85%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl, pH 8.0, 0.4 M Urea, 10% Glycerol
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
