LSBio
Human FCGR3A / CD16A Protein (Recombinant His)

Human FCGR3A / CD16A Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all FCGR3A antibodies →
$267.00each
Catalog Number: LS-G1842-20

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Overview

Description
Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A), also known as CD16A. This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. FCGR3A requires association of the gamma subunit of Fc epsilon RI or the zeta subunit of the TCR-CD3 complex for cell surface expression. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Recombinant human FCGR3A protein, fused to His-tag at N-terminus, was expressed in E.coli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CD16A | CD16a antigen | CD16 | FcgammaRIIIA | FCGR3A | FCR-10 | FCRIII | Fc gamma receptor III-A | Fc-gamma RIII | Fc-gamma RIII-alpha | FCG3 | IGFR3 | Fc- gamma riii | Fc-gamma receptor IIIb (CD16) | Fc-gamma RIIIa | FCGR3 | FCRIIIA | Neutrophil-specific antigen NA | Igg fc receptor iii-1 | IgG Fc receptor III-2 | Igg fc receptors iii-1 | FCGRIII
Origin Species
Human
NCBI GenBank
NM_000569|NP_000560.5
SwissProt
P08637

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
118-208aa|M RGSHHHHHHG MASMTGGQQM GRDLYDDDDK DRWGSHMRTE DLPKAVVFLE
61PQWYRVLEKD SVTLKCQGAY SPEDNSTQWF HNESLISSQA SSYFIDAATV DDSGEYRCQT
121NLSTLSDPVQ LEVHIGWLLL QAPRWVFKEE DPIHLRCHSW KNTALHKVTY LQNGKGRKYF
181HHNSDFYIPK ATLKDSGSYF CRGLFGSKNV SSETVNITIT QGLAVSTISS FFPPGYQ

237 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.