EREG / Epiregulin Antibody
Catalog Number: LS-C778687-100
100 µL / $365.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin
Reactivity: Human, Mouse, Rat
Format: Liquid
Human EREG / Epiregulin Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$288.00each
Catalog Number: LS-G136250-5
Catalog Number: LS-G136250
For bulk orders or custom formulations:
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- Description
- Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant Human Epiregulin is a 5.6 kDa monomeric protein, containing 50 amino residues, which corresponds to the mature secreted Epiregulin sequence.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Epiregulin | EREG | Proepiregulin | ER
- Origin Species
- Human
- NCBI GenBank
- NM_001432
- SwissProt
- O14944
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- 5.6 kDa
- Protein Type
- Recombinant
- Amino Acid Sequence
1MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL
50 aa
Format
- Purity
- >98%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile filtered solution, no additives.
- Animal Free
- Yes
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: Short term: Room temperature; Long term: -20°C to -80°C. After reconstitution: Short term: 4°C; Long term: Aliquot and store with a carrier protein at -20°C to -80°C. Avoid freeze thaw cycles. Microcentrifuge before opening.
