EGFR Antibody
Catalog Number: LS-C123475-50
50 µg / $499.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Human EGFR Protein (Recombinant His, C-Terminal)
ProteinLSBio Guarantee
| Expression System | Chinese Hamster Ovary |
| Format: | Lyophilized |
$302.00each
Catalog Number: LS-G27253-10
Catalog Number: LS-G27253
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- EGF Receptor,also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. It binds to a subset of EGF family ligands, including EGF, TGF-alpha, amphiregulin, EPGN, BTC, EREG and HBEGF. Ligand binding triggers receptor homo- or hetero-dimerization, which induces downstream kinase activation, tyrosine phosphorylation and cell signaling. EGF receptor signaling has been shown to regulate cell proliferation, differentiation, motility and apoptosis.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- EGFR | EGF Receptor | ERBB | ERBB1 | MENA | PIG61 | Proto-oncogene c-ErbB-1 | V-erb-b homolog | EGF-R | HER1
- Origin Species
- Human
- NCBI GenBank
- NM_005228|NP_005219.2
- SwissProt
- P00533
Protein
- Expression System
- Chinese Hamster Ovary
- Fusion Tag
- Hexahistidine Tag
- Molecular Weight
- 95-115 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1aa25-645|L EEKKVCQGTS NKLTQLGTFE DHFLSLQRMF NNCEVVLGNL EITYVQRNYD61LSFLKTIQEV AGYVLIALNT VERIPLENLQ IIRGNMYYEN SYALAVLSNY DANKTGLKEL121PMRNLQEILH GAVRFSNNPA LCNVESIQWR DIVSSDFLSN MSMDFQNHLG SCQKCDPSCP181NGSCWGAGEE NCQKLTKIIC AQQCSGRCRG KSPSDCCHNQ CAAGCTGPRE SDCLVCRKFR241DEATCKDTCP PLMLYNPTTY QMDVNPEGKY SFGATCVKKC PRNYVVTDHG SCVRACGADS301YEMEEDGVRK CKKCEGPCRK VCNGIGIGEF KDSLSINATN IKHFKNCTSI SGDLHILPVA361FRGDSFTHTP PLDPQELDIL KTVKEITGFL LIQAWPENRT DLHAFENLEI IRGRTKQHGQ421FSLAVVSLNI TSLGLRSLKE ISDGDVIISG NKNLCYANTI NWKKLFGTSG QKTKIISNRG481ENSCKATGQV CHALCSPEGC WGPEPRDCVS CRNVSRGREC VDKCNLLEGE PREFVENSEC541IQCHPECLPQ AMNITCTGRG PDNCIQCAHY IDGPHCVKTC PAGVMGENNT LVWKYADAGH601VCHLCHPNCT YGCTGPGLEG CPTNGPKIPS HHHHHH
636 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
