Overview

Description

I-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant Human I-TAC is an 8.3 kDa protein containing 73 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

Category

Proteins & Peptides > Proteins > Recombinant Proteins

Alternative Names

Beta-R1 | Chemokine h174 | Chemokine ip-9 | Chemokine itac | H174 | I-TAC | IP9 | ITAC | IP-9 | SCYB11 | Small inducible cytokine B11 | B-R1 | C-X-C motif chemokine 11 | CXCL11 | SCYB9B | Small-inducible cytokine B11

Origin Species

Human

NCBI GenBank

NM_005409

SwissProt

O14625