LSBio
Human CSF2 / GM-CSF Protein (Recombinant)

Human CSF2 / GM-CSF Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
See all CSF2 antibodies →
$2707.00each
Catalog Number: LS-G27039-1

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Overview

Description
Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF), a hematopoietic growth factor, is mainly involved in granulopoiesis and monocytopoiesis. It is produced by T-cells and macrophages in response to antigens, and by endothelial cells and fibroblasts following induction of various cytokines. A monomeric protein of 127 amino acidswith six glycosylation sites and two intra disulfide bonds, glycosylated and non-glycosylated hGM-CSFs show similar biological activities. Other than its connection to the growth and development of granulocytes and macrophages, it is also indispensable for the proliferation of erythroid and megakaryocytic cells. Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rhGM-CSF) produced in P. pastoris a glycosylated polypeptide. A fully biologically active molecule, rhGM-CSF has a molecular mass of 26-32kDa analyzed by SDS-PAGE and is obtained by refolding and chromatographic techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Colony-stimulating factor | CSF | CSF2 | GM-CSF | Molgramostin | GMCSF
Origin Species
Human
NCBI GenBank
NM_000758|NP_000749.2
SwissProt
P04141

Protein

Expression System
Other
Molecular Weight
26-32 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL
61ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF
121DCWEPVQE

128 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from 10 mM PB, pH 7.0.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 1 year. Upon reconstitution, store at 4°c for up to 4 weeks or at -20°c for up to 6 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.