LSBio
Human CSF1 / MCSF Protein (Recombinant)

Biological Activity M-CSF, Human stimulates cell proliferation of M-NFS-60 cells. The ED 50 for this effect is less than 5ng/mL.

Human CSF1 / MCSF Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
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$302.00each
Catalog Number: LS-G27051-10

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Overview

Description
Human Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CSF-1 | MCSF | M-CSF | CSF1 | Lanimostim | CSFM
Origin Species
Human
NCBI GenBank
NM_000757|NP_000748.3
SwissProt
P09603

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
32-40 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1EEVSEYCSHM IGSGHLQSLQ RLIDSQMETS CQITFEFVDQ EQLKDPVCYL KKAFLLVQDI
61MEDTMRFRDN TPNAIAIVQL QELSLRLKSC FTKDYEEHDK ACVRTFYETP LQLLEKVKNV
121FNETKNLLDK DWNIFSKNCN NSFAECSSQG HERQSEGS

158 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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