LSBio
Human CRYGS Protein (Recombinant His)

Human CRYGS Protein (Recombinant His)

Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all CRYGS antibodies →
$267.00each
Catalog Number: LS-G1426-20

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Overview

Description
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated alplha, beta and gamma. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. CRYGS, also known as beta-crystallin S, is exists as a monomer which does not aggregate. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. Recombinant human CRYGS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Beta-crystallin S | Crystallin | gamma S | gamma 8 | Gamma-S-crystallin | Gamma-crystallin S | CRYG8 | CRYGS | GRYG8
Origin Species
Human
NCBI GenBank
AL133079
SwissProt
P22914

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
11-178aa|MG SSHHHHHHSS GLVPRGSHMG SHMSKTGTKI TFYEDKNFQG RRYDCDCDCA
61DFHTYLSRCN SIKVEGGTWA VYERPNFAGY MYILPQGEYP EYQRWMGLND RLSSCRAVHL
121PSGGQYKIQI FEKGDFSGQM YETTEDCPSI MEQFHMREIH SCKVLEGVWI FYELPNYRGR
181QYLLDKKEYR KPIDWGAASP AVQSFRRIVE

210 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 0.1 M NaCl, 1 mM DTT, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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