Complement C1R Antibody
Catalog Number: LS-C761077
4 sizes / from $261.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Human Complement C5 Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$294.00each
Catalog Number: LS-G137917-10
Catalog Number: LS-G137917
For bulk orders or custom formulations:
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- Description
- Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 a-chain. Human C5a has four a-helices plus three intrachain disulfide bonds that create a triple loop structure. Human C5a is 60% and 54% aa identical to mouse and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a nonsignaling GPCR termed C5L2. Activation of Cd88 results in neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Anaphylatoxin C5a analog | C5 | CPAMD4 | Complement C5 | Complement component 5
- Origin Species
- Hu
- NCBI GenBank
- NM_001735
- SwissProt
- P01031
Protein
- Expression System
- E.coli
- Protein Type
- Recombinant
- Amino Acid Sequence
1STLQKKIEEI AAKYKHSVVK KCCYDGACVN NDETCEQRAA RISLGPRCIK AFTECCVVAS61QLRANISHKD MQLGR
75 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconj
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
