CDK2AP1 / DOC1 Antibody
Catalog Number: LS-C416003
2 sizes / from $312.00
Antibody: Rabbit Polyclonal
Applications: Western Blot
Reactivity: Human, Mouse
Format: Liquid
Human CDK2AP1 / DOC1 Protein (Recombinant His)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$260.00each
Catalog Number: LS-G701-20
Catalog Number: LS-G701
For bulk orders or custom formulations:
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- Description
- CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CDK2AP1 | Doc-1 | DORC1 | Deleted in oral cancer 1 | Deleted in oral cancer-1 | p12DOC-1 | ST19 | CDK2-associated protein 1 | CDKAP1 | DOC1
- Origin Species
- Human
- NCBI GenBank
- NM_004642|NP_004633.1
- SwissProt
- O14519
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
11-115aa|MR GSHHHHHHGM ASMTGGQQMG RDLYDDDDKD RWGSHMSYKP NLAAHMPAAA61LNAAGSVHSP STSMATSSQY RQLLSDYGPP SLGYTQGTGN SQVPQSKYAE LLAIIEELGK121EIRPTYAGSK SAMERLKRGI IHARGLVREC LAETERNARS
160 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 2mM DTT.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
