CDA / Cytidine Deaminase Antibody
Catalog Number: LS-C210982
2 sizes / from $300.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity: Human
Format: Liquid
Human CDA / Cytidine Deaminase Protein (Recombinant His)
ProteinLSBio Guarantee
| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$267.00each
Catalog Number: LS-G961-20
Catalog Number: LS-G961
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2-deoxycytidine for uMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Cytidine aminohydrolase | Cytidine deaminase | CDA | Small cytidine deaminase | CDD | Cytosine nucleoside deaminase
- Origin Species
- Human
- NCBI GenBank
- NM_001785|NP_001776.1
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
11-146aa|MG SSHHHHHHSS GLVPRGSHMA QKRPACTLKP ECVQQLLVCS QEAKQSAYCP61YSHFPVGAAL LTQEGRIFKG CNIENACYPL GICAERTAIQ KAVSEGYKDF RAIAIASDMQ121DDFISPCGAC RQVMREFGTN WPVYMTKPDG TYIVMTVQEL LPSSFGPEDL QKTQ
174 aa
Format
- Purity
- >90%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl, pH 8.0, 100 mM NaCl, 2 mM EDTA, 1 mM DTT, 40% Glycerol
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
