LSBio
Human CD36 Protein (Recombinant Fc, C-terminus)

Human CD36 Protein (Recombinant Fc, C-terminus)

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Expression SystemOther
Format:Lyophilized
See all CD36 antibodies →
$283.00each
Catalog Number: LS-G137860-10

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Overview

Description
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1,oxidized lowdensity lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, β amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparuminfected erythrocytes. CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Cluster determinant 36 | FAT | Fatty acid translocase | Glycoprotein IIIb | gp4 | GPIIIB | GPIV | PAS-4 protein | PAS IV | PASIV | Platelet collagen receptor | Platelet glycoprotein IV | SCARB3 | Thrombospondin receptor | BDPLT10 | CD36 | CD36 antigen | CHDS7 | gp3B | PAS-4 | Platelet glycoprotein 4
Origin Species
Human
NCBI GenBank
NM_000072
SwissProt
P16671

Protein

Expression System
Other
Fusion Tag
Human IgG1 Fc Tag
Protein Type
Recombinant
Amino Acid Sequence
1GDLLIQKTIK KQVVLEEGTI AFKNWVKTGT EVYRQFWIFD VQNPQEVMMN SSNIQVKQRG
6161PYTYRVRF LAKENVTQDA EDNTVSFLQP NGAIFEPSLS VGTEADNFTV LNLAVAAASH
121IYQNQFVQMI LNSLINKSKS SMFQVRTLRE LLWGYRDPFL SLVPYPVTTT VGLFYPYNNT
181ADGVYKVFNG KDNISKVAII DTYKGKRNLS YWESHCDMIN GTDAASFPPF VEKSQVLQFF
241SSDICRSIYA VFESDVNLKG IPVYRFVLPS KAFASPVENP DNYCFCTEKI ISKNCTSYGV
301LDISKCKEGR PVYISLPHFL YASPDVSEPI DGLNPNEEEH RTYLDIEPIT GFTLQFAKRL
361QVNLLVKPSE KIQVLKNLKR NYIVPILWLN ETGTIGDEKA NMFRSQVTGK INVDDIEGRM
421DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK
481FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK
541TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT
601PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK

653 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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