CCL13 / MCP4 Antibody
Catalog Number: LS-C781357-100
100 µL / $365.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Liquid
Human CCL13 / MCP4 Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$297.00each
Catalog Number: LS-G131277-25
Catalog Number: LS-G131277
For bulk orders or custom formulations:
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- Description
- Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils, monocytes, and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells, and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis. The expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy. The recombinant construct corresponds to the "short-chain" of CCL13 spanning amino acids 24 - 98.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- C-C motif chemokine 13 | CKb10 | MCP-4 | MCP4 | Monocyte chemotactic protein 4 | New CC chemokine 1 | Small-inducible cytokine A13 | NCC1 | CCL13 | CK-beta-10 | NCC-1 | SCYA13
- Origin Species
- Human
- NCBI GenBank
- NM_005408
- SwissProt
- Q99616
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- ~9 kDa
- Protein Type
- Recombinant
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1.0 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from sterile PBS, pH 7.5, 100 mM NaCl
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- The lyophilized protein is stable for up to 1 year at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2°C to 8°C for 1 month, or at -20°C for 6 months, with a carrier protein without detectable loss of activity. Avoid freeze/thaw cycles.
