LSBio
Human CAPG Protein (Recombinant)

Human CAPG Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$260.00each
Catalog Number: LS-G661-20

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Overview

Description
Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. Recombinant human CAPG was expressed in E.coli and purified by using conventional chromatography techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
AFCP | Actin-regulatory protein CAP-G | CAPG | Actin regulatory protein CAP-G | Gelsolin-like capping protein | MCP | Macrophage capping protein | Macrophage-capping protein
Origin Species
Human
NCBI GenBank
NM_001747|NP_001738.2
SwissProt
P40121

Protein

Expression System
Escherichia coli (Prokaryotic)
Protein Type
Recombinant
Amino Acid Sequence
11-348aa|MY TAIPQSGSPF PGSVQDPGLH VWRVEKLKPV PVAQENQGVF FSGDSYLVLH
61NGPEEVSHLH LWIGQQSSRD EQGACAVLAV HLNTLLGERP VQHREVQGNE SDLFMSYFPR
121GLKYQEGGVE SAFHKTSTGA PAAIKKLYQV KGKKNIRATE RALNWDSFNT GDCFILDLGQ
181NIFAWCGGKS NILERNKARD LALAIRDSER QGKAQVEIVT DGEEPAEMIQ VLGPKPALKE
241GNPEEDLTAD KANAQAAALY KVSDATGQMN LTKVADSSPF ALELLISDDC FVLDNGLCGK
301IYIWKGRKAN EKERQAALQV AEGFISRMQY APNTQVEILP QGRESPIFKQ FFKDWK

356 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl, pH 8.0, 1 mM DTT, 10% Glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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